Wednesday, December 7, 2022
BIO130 - Molecules & Medicines
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Syllabus

 

 

 

COURSE OUTLINE

FALL 2010

                                                                           Lecture Syllabus    

   BIO 130/Molecules & Medicines      

           

  1. Hanson, B. Understanding Medicinal Plants: Their Chemistry and Therapeutic Action. Binghamton, NY: The Haworth Press, 2005.
  2. Sackheim, G. I. Introduction to Chemistry for Biology Students.  San Francisco, CA: Benjamin/Cummings, 2007.
  3. Balick, M. J. & Cox, P. A. Plants, People, and Culture. The Science of Ethnobotany.  NY: Scientific American Library, 1997.

Week

Topic

Readings

1.

Plants & Medicines – Aloe & Willow

Connecting Chemistry to Botany

Video:  Ancient Drugs  VVXV BL65.D7 A5 1998

Chapter 1 (Txt 1)

Plants That Heal

(Balick & Cox)

2.

Nature and Significance in Botany

Atoms, Bonds, and Molecules

Video: Chemical Foundations of Life QH315. 3. C53

Chapter 3 (Txt 1)

3.

Chemicals of Life – Organic Molecules

Carbohydrates, Proteins, Lipids, Nucleic Acids

Video: Proteins: building blocks of life (vol.10) QH313.C84

Chapter 3 (Txt 1)

Chapter 4 (Txt 1)

4.

Human Physiology and Chemical Communications – Endorphins, hormones, and neurotransmitters

Video: The Chemistry of  Life: hormones and the endocrine system QP187.C53 Lecture Test 1

History of Medicine &Medicinal Plant Project

Chapter 7

(Txt 1)

5.

3-D Molecules of Life (Ethnobotanical Research Project)

Research

Using 3-D Theatre

6.

Enzymes and their Functions (1)

Video: The Magic of Enzymes QP601. M34

Handout

Chapter 6 (Txt 1)

7.

Drug Module (2)

Handout

Chapter 6 (Txt 1)

8.

Drug Module (3)

Vioxx Recall and FDA

Handout

Ch. 6 & 7 (Txt 1)

9.

Visit to 3-D theatre

3-D Structures & Functions– 3-D Molecules of Choice

Lecture Test 2 +  Modern Drug & Mode of Action Project

Research Protein Data Base for a Molecule of Significance

10.

Traditional Medicines vs. Modern Medicines - Yew, Yam, Digitalis, and others

Chapter 5 (Txt 1)

Readings from Balick & Cox

11.

History & Cultural Use of Plants

Doctrine of Signature and Use of Plants for Food & Medicines

Video: Plant Wars a global view of natural plants            

                                     RM431.M37 P63

Chapter 7 (Txt 1)

Readings from Balick & Cox

12.

Medicinal Plants and Human Health

-alkaloids and aromatic

 Video: Nature’s Pharmacy -  RM437. M37 N37

Chapter 7 (Txt 1)

13.

Phytotherapy and Medicinal Plants

-          flavonoids, terpenes, and glycosides

                    Video: Plant Defenses SB 933.2. P5

Chapter 7 (Txt 1)

Readings from Balick & Cox

14.

Drug Recall Project PPT

research

15.

Pulling-it-together

Lecture Test 3


 

                                                               

    

                                                              COURSE OUTLINE

                                                            Laboratory Syllabus

BIO 130/Molecules & MedicinesInquiry-based Activities

  1. Prabhakar, K. Laboratory Manual: Molecules & Medicines, NCC Printing Press, Garden City, NY, spring 2009.
  2. Sackheim, G. I. Introduction to Chemistry for Biology Students.  San Francisco, CA: Benjamin/Cummings, 2007.  

Week

Topic

Resource

1.

Safety Orientation

Introduction to Scientific Processes

                                     Slide show:  Medicinal Plants RS 164. M44

Unit 1

2.

Investigating  Taxonomy of Medicinal Plants

Video: Plant Kingdom - QK51. P43

Unit 2

(Field Trip)

3.

Modeling Atom, Elements, Molecules (water),

and Functional Groups

Significance of Chemicals in Biology/Botany

Unit 3

Text 2

4.

                            Edible Plant Parts  and Organic Molecules

Video: In the presence of healers conversations with

ethnobotanist Paul Cox - GN476.73 15

Unit 4

Text 2

5.

Testing Chemicals in Edible Plant Parts

Mapping Chemical Communications in Human Body –

Mode of Action of Neurotransmitter (Caffeine) on Brine Shrimp

Video: Scientific Method- Q175.32. R45 S35

Unit 6

Scientific Method

Text 2

6.

Catalase Functions (Enzyme Kinetics)

Reading Unit 7

Unit 8

7.

Enzymes and Modern Medicines - Exercise Using Models – Induced Fit vs. Lock & Key

Unit 7 & 8

8.

Online Activities – 3-D Organic Molecules of Biological Importance

Visit to 3-D Theatre

Lab Midterm

Research

9.

 Mode of Action Models – Modern vs. Traditional Medicines

Willow vs. Aspirin vs. Vioxx

Video: Herbal Remedies – RM 666. H33 H4

Exploring Facts & Myths of Traditional Medicines

Administering Ethnobotanical Surveys and Conducting FDA

Research-Ginkgo biloba, Echinacea, Garlic, Black cohosh etc.

Unit 9

(Field Trip)

Readings from Balick & Cox

10.

Lab Midterm

Designing Independent Research Project

Molecules & their effect on Plants or Animals

                       

Scientific Method

Background Research

11.

                Extracting Pigments – Chlorophylls, carotenes, and xanthophylls

Pigments promoting good health (Chromatography)

Unit 11

12.

Video - “The Shaman’s Apprentice”

Comparing Indian, Greek, Chinese, and Japanese Tea(s)

Testing Decoctions for pH

    Anticoagulant Effect of Tea – Sheep Blood Exercise (Spectrophotometry)

Unit 10

13.

Antimicrobial Properties of Botanicals

-          testing garlic, ginger, lavender, oregano, and mint

-          structure and function of active ingredients

Unit 12

14.

Pulling-it-together

Ethnobotanical Data Analysis; Final Draft of Independent Project Due; Discussion on Evaluation of Evidence

Research Project

15.

PowerPoint Presentations

Colloquium Session & Lab Final


 

                                                       

  
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